Patients with gout (odds ratio [OR], 2.98) and vasculitis (OR, 2.58) had the highest odds of cardiovascular disease hospitalization, while patients with OA were associated with lower odds (OR, 0.88).

Racial disparities were evident across various rheumatic disease categories, with the exception of patients with rheumatoid arthritis or systemic lupus erythematosus/mixed connective tissue disease. Among those without rheumatic diseases, Alaska Native and American Indian individuals exhibited the lowest rates of cardiovascular disease hospitalization. However, rates of cardiovascular hospitalization for Alaska Native and American Indian patients with OA or gout fell in between those of White patients (the lowest) and individuals of other races (the highest).

Study limitations included potential selection bias towards patients with more severe rheumatic disease, lack of outpatient data, limited racial and gender categories, heterogeneity in grouped diseases, and the inability to establish causation.

“Our finding that the association of rheumatic disease diagnosis and cardiovascular disease hospitalization var­ies by race is novel,” study authors concluded.

Disclosure: This research was supported by the Accelerating Medicines Partnership in

Rheumatoid Arthritis and Lupus Network. Some study authors declared affiliations with biotech, pharmaceutical, and/or device companies. Please see the original reference for a full list of disclosures.


Ferucci ED, Holck P. An assessment of cardiovascular disease hospitalizations and disparities by race in patients with rheumatic disease hospitalizations in Alaska, 2015-2018BMC Rheumatol. Published online February 18, 2024. doi:10.1186/s41927-024-00377-8